Cargando…

In vitro and ex vivo evaluation of a multi-epitope heparinase vaccine for various malignancies

Previous studies have indicated that heparanase (Hpa) might represent a candidate universal tumor-associated antigen. However, vaccine therapy targeting only one cytotoxic T lymphocyte (CTL) epitope is suboptimal in preventing cancer. In the present study, we designed heparanase multi-epitope vaccin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Xu-Dong, Guo, Shu-Liang, Wang, Guo-Zhen, Li, Ning, Wu, Yu-Yun, Fang, Dian-Chun, Fan, Ya-Han, Yang, Shi-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317872/ https://www.ncbi.nlm.nih.gov/pubmed/24152338 http://dx.doi.org/10.1111/cas.12308

Ejemplares similares

Role of heparinase in the gastrointestinal dysfunction of sepsis (Review)
por: Chen, Ting-Ting, et al.
Publicado: (2022)

Discovery of exolytic heparinases and their catalytic mechanism and potential application
por: Zhang, Qingdong, et al.
Publicado: (2021)

Structure-based engineering of heparinase I with improved specific activity for degrading heparin
por: Zhang, Chuan, et al.
Publicado: (2019)

Heparinase Digestion of 3-O-Sulfated Sequences: Selective Heparinase II Digestion for Separation and Identification of Binding Sequences Present in ATIII Affinity Fractions of Bovine Intestinal Heparins
por: Mourier, Pierre
Publicado: (2022)

Isolation, Purification, and Characterization of Heparinase from Streptomyces variabilis MTCC 12266
por: Singh, Vineeta, et al.
Publicado: (2019)

82 Heparinase-Native Thromboelastometry Detects Hypercoagulability in COVID-19 Disease
por: Maher, P.J., et al.
Publicado: (2021)

Cloning, Expression, and Characterization of a Highly Stable Heparinase I from Bacteroides xylanisolvens
por: Pei, Jia-Lu, et al.
Publicado: (2023)

Identification and characterization of a novel heparinase PCHepII from marine bacterium Puteibacter caeruleilacunae
por: Lu, Danrong, et al.
Publicado: (2023)

Isolation and characterization of HepP: a virulence-related Pseudomonas aeruginosa heparinase
por: Dzvova, Nyaradzo, et al.
Publicado: (2017)

A highly active heparinase I from Bacteroides cellulosilyticus: Cloning, high level expression, and molecular characterization
por: Gao, Li-Wei, et al.
Publicado: (2020)

Novel Thermostable Heparinase Based on the Genome of Bacteroides Isolated from Human Gut Microbiota
por: Zhang, Chuan, et al.
Publicado: (2022)

A Simple, Rapid, and Effective Heparinase Protocol to Enable Nucleic Acid Study from Frozen Heparinized Plasma
por: Afruza, Rownock, et al.
Publicado: (2023)

The unremarkable alveolar epithelial glycocalyx: a thorium dioxide-based electron microscopic comparison after heparinase or pneumolysin treatment
por: Timm, Sara, et al.
Publicado: (2023)

Formulation of Polymers-Based Methotrexate Patches and Investigation of the Effect of Various Penetration Enhancers: In Vitro, Ex Vivo and In Vivo Characterization
por: Latif, Muhammad Shahid, et al.
Publicado: (2022)

Heparinase treatment of heparin-contaminated plasma from coronary artery bypass grafting patients enables reliable quantification of microRNAs
por: Kondratov, Kirill, et al.
Publicado: (2016)

Update of in vitro, in vivo and ex vivo fluoro-edenite effects on malignant mesothelioma: A systematic review (Review)
por: Filetti, Veronica, et al.
Publicado: (2020)

Downregulation of heparanase by RNA interference inhibits invasion and tumorigenesis of hepatocellular cancer cells in vitro and in vivo
por: Xiong, Zhen, et al.
Publicado: (2022)

The effects of in vivo and ex vivo various degrees of cold exposure on erythrocyte deformability and aggregation
por: Erken, Gülten, et al.
Publicado: (2011)

Assays of CFTR Function In Vitro, Ex Vivo and In Vivo
por: Ramalho, Anabela S., et al.
Publicado: (2022)

In Vitro, Ex Vivo, and In Vivo Models for the Study of Pemphigus
por: Lotti, Roberta, et al.
Publicado: (2022)

Establishment of an easy and straight forward heparinase protocol to analyse circulating and myocardial tissue micro-RNA during coronary artery-bypass-graft surgery
por: Engler, Andrea, et al.
Publicado: (2018)

In vitro, ex vivo, and in vivo models for dental pulp regeneration
por: Piglionico, Sofia Silvia, et al.
Publicado: (2023)

In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin
por: Jørgensen, Jacob Rune, et al.
Publicado: (2020)

In vivo, ex vivo and in vitro dasatinib activity in chronic lymphocytic leukemia
por: Giannopoulos, Krzysztof, et al.
Publicado: (2021)

Antihyperglycemic Effect of Lavandula pedunculata: In Vivo, In Vitro and Ex Vivo Approaches
por: Boutahiri, Salima, et al.
Publicado: (2021)

In Vitro, In Vivo and Ex Vivo Models for Peripheral Nerve Injury and Regeneration
por: Li, Andrew, et al.
Publicado: (2022)

Genetically encoded phosphatidylserine biosensor for in vitro, ex vivo and in vivo labelling
por: Dirvelyte, Eimina, et al.
Publicado: (2023)

Lazertinib improves the efficacy of chemotherapeutic drugs in ABCB1 or ABCG2 overexpression cancer cells in vitro, in vivo, and ex vivo
por: Fan, Yingfang, et al.
Publicado: (2022)

Linarin Inhibits the Acetylcholinesterase Activity In-vitro and Ex-vivo
por: Feng, Xinchi, et al.
Publicado: (2015)

Optical Characterization of Sodium Fluorescein In Vitro and Ex Vivo
por: Xu, Ran, et al.
Publicado: (2021)

In vitro and ex vivo modeling of enteric bacterial infections
por: Taebnia, Nayere, et al.
Publicado: (2022)

Antifungal effectiveness of various intracanal medicaments against Candida albicans: an ex-vivo study
por: Chua, Eu Gene, et al.
Publicado: (2014)

Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology
por: Larsson, Alex T, et al.
Publicado: (2023)

The effect of various in-vitro and ex-vivo parameters on irrigant flow and apical pressure using manual syringe needle irrigation: Systematic review
por: Teja, Kavalipurapu Venkata, et al.
Publicado: (2022)

The Characterization of chIFITMs in Avian Coronavirus Infection In Vivo, Ex Vivo and In Vitro
por: Steyn, Angela, et al.
Publicado: (2020)

Comparative Molecular Analysis of Cancer Behavior Cultured In Vitro, In Vivo, and Ex Vivo
por: Hum, Nicholas R., et al.
Publicado: (2020)

Biomedical applications of copper-free click chemistry: in vitro, in vivo, and ex vivo
por: Kim, Eunha, et al.
Publicado: (2019)

Multi-Epitope Vaccine Design Using an Immunoinformatic Approach for SARS-CoV-2
por: Feng, Ye, et al.
Publicado: (2021)

Multi-tracer and multiparametric PET imaging to detect the IDH mutation in glioma: a preclinical translational in vitro, in vivo, and ex vivo study
por: Clément, Alexandra, et al.
Publicado: (2022)

Ex Vivo(1)H NMR study of pituitary adenomas to differentiate various immunohistochemical subtypes
por: Ijare, Omkar B., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9bnn5bpe5ov2rssg0enuqosn01