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Reoxygenation from chronic hypoxia promotes metastatic processes in pancreatic cancer through the Hedgehog signaling

Pancreatic ductal adenocarcinoma (PDAC) is among the most deadly types of malignancies because of its high ability to metastasize. PDAC is thought to be under hypoxic condition. Therefore, to investigate the mechanism of metastatic processes, chronic-hypoxia-resistant PDAC cells were newly generated...

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Detalles Bibliográficos
Autores principales: Morifuji, Yoshihiro, Onishi, Hideya, Iwasaki, Hironori, Imaizumi, Akira, Nakano, Kenji, Tanaka, Masao, Katano, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317936/
https://www.ncbi.nlm.nih.gov/pubmed/24397700
http://dx.doi.org/10.1111/cas.12348