Cargando…

Nuclear export signal within CALM is necessary for CALM-AF10-induced leukemia

The CALM–AF10 fusion gene, which results from a t(10;11) translocation, is found in a variety of hematopoietic malignancies. Certain HOXA cluster genes and MEIS1 genes are upregulated in patients and mouse models that express CALM-AF10. Wild-type clathrin assembly lymphoid myeloid leukemia protein (...

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, Mai, Yamagata, Kazutsune, Shino, Mika, Aikawa, Yukiko, Akashi, Koichi, Watanabe, Toshio, Kitabayashi, Issay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317939/
https://www.ncbi.nlm.nih.gov/pubmed/24397609
http://dx.doi.org/10.1111/cas.12347