Heat shock protein 90 inhibitor NVP-AUY922 exerts potent activity against adult T-cell leukemia–lymphoma cells

Adult T-cell leukemia–lymphoma (ATL), an aggressive neoplasm etiologically associated with HTLV-1, is a chemoresistant malignancy. Heat shock protein 90 (HSP90) is involved in folding and functions as a chaperone for multiple client proteins, many of which are important in tumorigenesis. In this stu...

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Detalles Bibliográficos
Autores principales: Taniguchi, Hiroaki, Hasegawa, Hiroo, Sasaki, Daisuke, Ando, Koji, Sawayama, Yasushi, Imanishi, Daisuke, Taguchi, Jun, Imaizumi, Yoshitaka, Hata, Tomoko, Tsukasaki, Kunihiro, Uno, Naoki, Morinaga, Yoshitomo, Yanagihara, Katsunori, Miyazaki, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317953/
https://www.ncbi.nlm.nih.gov/pubmed/25263741
http://dx.doi.org/10.1111/cas.12540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317953/
https://www.ncbi.nlm.nih.gov/pubmed/25263741
http://dx.doi.org/10.1111/cas.12540

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