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Preparation and characterization of anti-tissue factor single-chain variable fragment antibody for cancer diagnosis

Tissue factor (TF), which serves as the initiator of the extrinsic blood coagulation cascade, has been found to be overexpressed in various solid tumors, especially brain tumors, pancreatic cancer, and gastric cancer. Overexpression of TF is considered to contribute to the high incidence of thrombot...

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Detalles Bibliográficos
Autores principales: Sato, Ryuta, Obonai, Toshifumi, Tsumura, Ryo, Tsumoto, Kouhei, Koga, Yoshikatsu, Yasunaga, Masahiro, Matsumura, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317963/
https://www.ncbi.nlm.nih.gov/pubmed/25311092
http://dx.doi.org/10.1111/cas.12557