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Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase–phosphoinositide 3-kinase-dependent anti-apoptotic signaling

Angiopoietin-like protein 2 (ANGPTL2) plays an important role in inflammatory carcinogenesis and tumor metastasis by activating tumor angiogenesis and tumor cell chemotaxis and invasiveness. However, it is unclear whether ANGPTL2 expression has an effect on tumor cell survival. Here, we explored tha...

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Detalles Bibliográficos
Autores principales: Horiguchi, Haruki, Endo, Motoyoshi, Miyamoto, Yuji, Sakamoto, Yasuo, Odagiri, Haruki, Masuda, Tetsuro, Kadomatsu, Tsuyoshi, Tanoue, Hironori, Motokawa, Ikuyo, Terada, Kazutoyo, Morioka, Masaki Suimye, Manabe, Ichiro, Baba, Hideo, Oike, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317964/
https://www.ncbi.nlm.nih.gov/pubmed/25287946
http://dx.doi.org/10.1111/cas.12554