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Antitumor effects of tyropeptin-boronic acid derivatives: New proteasome inhibitors

The proteasome degrades numerous regulatory proteins that are critical for tumor growth. Thus, proteasome inhibitors are promising antitumor agents. New proteasome inhibitors, such as tyropeptins and tyropeptin-boronic acid derivatives, have a potent inhibitory activity. Here we report the antitumor...

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Detalles Bibliográficos
Autores principales: Momose, Isao, Abe, Hikaru, Watanabe, Takumi, Ohba, Shun-ichi, Yamazaki, Kanami, Dan, Shingo, Yamori, Takao, Masuda, Tohru, Nomoto, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317970/
https://www.ncbi.nlm.nih.gov/pubmed/25251038
http://dx.doi.org/10.1111/cas.12542