Up-regulation of neural and cell cycle-related microRNAs in brain of amyotrophic lateral sclerosis mice at late disease stage

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by selective motor neuron degeneration in motor cortex, brainstem and spinal cord. microRNAs (miRNAs) are small non-coding RNAs that bind complementary target sequences and modulate gene expression; th...

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Detalles Bibliográficos
Autores principales: Marcuzzo, Stefania, Bonanno, Silvia, Kapetis, Dimos, Barzago, Claudia, Cavalcante, Paola, D’Alessandro, Sara, Mantegazza, Renato, Bernasconi, Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318136/
https://www.ncbi.nlm.nih.gov/pubmed/25626686
http://dx.doi.org/10.1186/s13041-015-0095-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318136/
https://www.ncbi.nlm.nih.gov/pubmed/25626686
http://dx.doi.org/10.1186/s13041-015-0095-0

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