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Lamins at the crossroads of mechanosignaling

The intermediate filament proteins, A- and B-type lamins, form the nuclear lamina scaffold adjacent to the inner nuclear membrane. B-type lamins confer elasticity, while A-type lamins lend viscosity and stiffness to nuclei. Lamins also contribute to chromatin regulation and various signaling pathway...

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Detalles Bibliográficos
Autores principales: Osmanagic-Myers, Selma, Dechat, Thomas, Foisner, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318140/
https://www.ncbi.nlm.nih.gov/pubmed/25644599
http://dx.doi.org/10.1101/gad.255968.114