Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5

Binding of the Hedgehog (Hh) protein signal to its receptor, Patched, induces accumulation of the seven-pass transmembrane protein Smoothened (Smo) within the primary cilium and of the zinc finger transcription factor Gli2 at the ciliary tip, resulting ultimately in Gli-mediated changes in nuclear g...

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Detalles Bibliográficos
Autores principales: Chong, Yong Chun, Mann, Randall K., Zhao, Chen, Kato, Masaki, Beachy, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318143/
https://www.ncbi.nlm.nih.gov/pubmed/25644602
http://dx.doi.org/10.1101/gad.252676.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318143/
https://www.ncbi.nlm.nih.gov/pubmed/25644602
http://dx.doi.org/10.1101/gad.252676.114

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