Cytokinesis breaks dicentric chromosomes preferentially at pericentromeric regions and telomere fusions

Dicentric chromosomes are unstable products of erroneous DNA repair events that can lead to further genome rearrangements and extended gene copy number variations. During mitosis, they form anaphase bridges, resulting in chromosome breakage by an unknown mechanism. In budding yeast, dicentrics gener...

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Detalles Bibliográficos
Autores principales: Lopez, Virginia, Barinova, Natalja, Onishi, Masayuki, Pobiega, Sabrina, Pringle, John R., Dubrana, Karine, Marcand, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318148/
https://www.ncbi.nlm.nih.gov/pubmed/25644606
http://dx.doi.org/10.1101/gad.254664.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318148/
https://www.ncbi.nlm.nih.gov/pubmed/25644606
http://dx.doi.org/10.1101/gad.254664.114

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