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Why does the hemolytic activity of silica predict its pro-inflammatory activity?

BACKGROUND: The hemolytic activity of inhaled particles such as silica has been widely investigated in the past and represents a usual toxicological endpoint to characterize particle reactivity despite the fact that red blood cells (RBCs) are not involved in the pathogenesis of pulmonary inflammatio...

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Detalles Bibliográficos
Autores principales: Pavan, Cristina, Rabolli, Virginie, Tomatis, Maura, Fubini, Bice, Lison, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318150/
https://www.ncbi.nlm.nih.gov/pubmed/25522817
http://dx.doi.org/10.1186/s12989-014-0076-y