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Short and Efficient Synthesis of Alkyl- and Aryl-Ortho-Hydroxy-Anilides and their Antibiotic Activity

Ortho-hydroxy-anilides are part of natural products like the new antibiotics platencin (A) and platensimycin (B). An important step in the total synthesis of these antibiotics or their derivatives is the preparation of the o-hydroxy-anilide partial structure. The presented method allows the preparat...

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Detalles Bibliográficos
Autores principales: Krauß, Jürgen, Plesch, Eva, Clausen, Sabine, Bracher, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientia Pharmaceutica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318158/
https://www.ncbi.nlm.nih.gov/pubmed/25853064
http://dx.doi.org/10.3797/scipharm.1401-19