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Platelet rich clots are resistant to lysis by thrombolytic therapy in a rat model of embolic stroke

BACKGROUND: Early recanalization of occluded vessels in stroke is closely associated with improved clinical outcome. Microbubble-enhanced sonothrombolysis is a promising therapy to improve recanalization rates and reduce the time to recanalization. Testing any thrombolytic therapy requires a model o...

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Detalles Bibliográficos
Autores principales: Tomkins, Amelia J, Schleicher, Nadine, Murtha, Lucy, Kaps, Manfred, Levi, Christopher R, Nedelmann, Max, Spratt, Neil J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318170/
https://www.ncbi.nlm.nih.gov/pubmed/25657829
http://dx.doi.org/10.1186/s13231-014-0014-y