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Preparation, In Vitro Characterization, and In Vivo Pharmacokinetic Evaluation of Respirable Porous Microparticles Containing Rifampicin

This study aimed to prepare and evaluate rifampicin microparticles for the lung delivery of rifampicin as respirable powder. The microparticles were prepared using chitosan by the spray-drying method and evaluated for aerodynamic properties and pulmonary drug absorption. To control the drug release,...

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Detalles Bibliográficos
Autores principales: Kundawala, Aliasgar, Patel, Vishnu, Patel, Harsha, Choudhary, Dhaglaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientia Pharmaceutica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318219/
https://www.ncbi.nlm.nih.gov/pubmed/25853075
http://dx.doi.org/10.3797/scipharm.1307-03