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Randomized non-inferiority and safety trial of dihydroartemisin-piperaquine and artesunate-amodiaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Cameroonian children

BACKGROUND: Artemether-lumefantrine and artesunate-amodiaquine are first-line treatment for uncomplicated malaria in Cameroon. No study has yet compared the efficacy of these drugs following the WHO recommended 42-day follow-up period. The goal of this study was to compare the clinical efficacy, tol...

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Detalles Bibliográficos
Autores principales: Nji, Akindeh M, Ali, Innocent M, Moyeh, Marcel N, Ngongang, Eric-Oliver, Ekollo, Aristide M, Chedjou, Jean-Paul, Ndikum, Valentine N, Evehe, Marie S, Froeschl, Guenter, Heumann, Christian, Mansmann, Ulrich, Ogundahunsi, Olumide, Mbacham, Wilfred F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318246/
https://www.ncbi.nlm.nih.gov/pubmed/25626448
http://dx.doi.org/10.1186/s12936-014-0521-2