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Bruchpilot and Synaptotagmin collaborate to drive rapid glutamate release and active zone differentiation

The active zone (AZ) protein Bruchpilot (Brp) is essential for rapid glutamate release at Drosophila melanogaster neuromuscular junctions (NMJs). Quantal time course and measurements of action potential-waveform suggest that presynaptic fusion mechanisms are altered in brp null mutants (brp(69)). Th...

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Detalles Bibliográficos
Autores principales: Paul, Mila M., Pauli, Martin, Ehmann, Nadine, Hallermann, Stefan, Sauer, Markus, Kittel, Robert J., Heckmann, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318344/
https://www.ncbi.nlm.nih.gov/pubmed/25698934
http://dx.doi.org/10.3389/fncel.2015.00029