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Magic Angle Spinning Nuclear Magnetic Resonance Characterization of Voltage-Dependent Anion Channel Gating in Two-Dimensional Lipid Crystalline Bilayers

[Image: see text] The N-terminus of the voltage-dependent anion channel (VDAC) has been proposed to contain the mechanistically important gating helices that modulate channel opening and closing. In this study, we utilize magic angle spinning nuclear magnetic resonance (MAS NMR) to determine the loc...

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Detalles Bibliográficos
Autores principales: Eddy, Matthew T., Andreas, Loren, Teijido, Oscar, Su, Yongchao, Clark, Lindsay, Noskov, Sergei Y., Wagner, Gerhard, Rostovtseva, Tatiana K., Griffin, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318587/
https://www.ncbi.nlm.nih.gov/pubmed/25545271
http://dx.doi.org/10.1021/bi501260r