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Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells
Disulfiram, a clinically used alcohol-deterrent has gained prominence as a potential anti-cancer agent due to its impact on copper-dependent processes. Few studies have investigated zinc effects on disulfiram action, despite it having high affinity for this metal. Here we studied the cytotoxic effec...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318799/ https://www.ncbi.nlm.nih.gov/pubmed/25557293 http://dx.doi.org/10.1016/j.bcp.2014.12.014 |