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Effects of early and late-onset treatment with carvedilol in an experimental model of aortic regurgitation
BACKGROUND: Beta-blockade is contraindicated in severe aortic regurgitation (AR) due to the fear of prolonging diastole and thus aggravate regurgitation. However, this has never been scientifically proven and positive effects of targeting the sympathetic system in AR has been demonstrated in several...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318827/ https://www.ncbi.nlm.nih.gov/pubmed/25674505 http://dx.doi.org/10.1186/s40064-015-0829-6 |