Cargando…

CDH13 promoter SNPs with pleiotropic effect on cardiometabolic parameters represent methylation QTLs

CDH13 encodes T-cadherin, a receptor for high molecular weight (HMW) adiponectin and low-density lipoprotein, promoting proliferation and migration of endothelial cells. Genome-wide association studies have mapped multiple variants in CDH13 associated with cardiometabolic traits (CMT) with variable...

Descripción completa

Detalles Bibliográficos
Autores principales: Putku, Margus, Kals, Mart, Inno, Rain, Kasela, Silva, Org, Elin, Kožich, Viktor, Milani, Lili, Laan, Maris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318987/
https://www.ncbi.nlm.nih.gov/pubmed/25543204
http://dx.doi.org/10.1007/s00439-014-1521-6