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CDH13 promoter SNPs with pleiotropic effect on cardiometabolic parameters represent methylation QTLs
CDH13 encodes T-cadherin, a receptor for high molecular weight (HMW) adiponectin and low-density lipoprotein, promoting proliferation and migration of endothelial cells. Genome-wide association studies have mapped multiple variants in CDH13 associated with cardiometabolic traits (CMT) with variable...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318987/ https://www.ncbi.nlm.nih.gov/pubmed/25543204 http://dx.doi.org/10.1007/s00439-014-1521-6 |