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Lysosomal Two-pore Channel Subtype 2 (TPC2) Regulates Skeletal Muscle Autophagic Signaling

Postnatal skeletal muscle mass is regulated by the balance between anabolic protein synthesis and catabolic protein degradation, and muscle atrophy occurs when protein homeostasis is disrupted. Autophagy has emerged as critical in clearing dysfunctional organelles and thus in regulating protein turn...

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Detalles Bibliográficos
Autores principales: Lin, Pei-Hui, Duann, Pu, Komazaki, Shinji, Park, Ki Ho, Li, Haichang, Sun, Mingzhai, Sermersheim, Mathew, Gumpper, Kristyn, Parrington, John, Galione, Antony, Evans, A. Mark, Zhu, Michael X., Ma, Jianjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319008/
https://www.ncbi.nlm.nih.gov/pubmed/25480788
http://dx.doi.org/10.1074/jbc.M114.608471