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Lysosomal Two-pore Channel Subtype 2 (TPC2) Regulates Skeletal Muscle Autophagic Signaling
Postnatal skeletal muscle mass is regulated by the balance between anabolic protein synthesis and catabolic protein degradation, and muscle atrophy occurs when protein homeostasis is disrupted. Autophagy has emerged as critical in clearing dysfunctional organelles and thus in regulating protein turn...
Autores principales: | Lin, Pei-Hui, Duann, Pu, Komazaki, Shinji, Park, Ki Ho, Li, Haichang, Sun, Mingzhai, Sermersheim, Mathew, Gumpper, Kristyn, Parrington, John, Galione, Antony, Evans, A. Mark, Zhu, Michael X., Ma, Jianjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319008/ https://www.ncbi.nlm.nih.gov/pubmed/25480788 http://dx.doi.org/10.1074/jbc.M114.608471 |
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