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Correlations between long inverted repeat (LIR) features, deletion size and distance from breakpoint in human gross gene deletions
Long inverted repeats (LIRs) have been shown to induce genomic deletions in yeast. In this study, LIRs were investigated within ±10 kb spanning each breakpoint from 109 human gross deletions, using Inverted Repeat Finder (IRF) software. LIR number was significantly higher at the breakpoint regions,...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319165/ https://www.ncbi.nlm.nih.gov/pubmed/25657065 http://dx.doi.org/10.1038/srep08300 |