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Estrogen mediated expression of nucleophosmin 1 in human endometrial carcinoma clinical stages through estrogen receptor-α signaling

BACKGROUND: Endometrial carcinoma is one of the most common gynecologic malignancies. Estrogen plays a critical role in its pathogenesis, but the underlying mechanism is not clear. Nucleophosmin 1 (NPM1), a multifunctional protein involved in many cellular activities, has been implicated in the tumo...

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Detalles Bibliográficos
Autores principales: Zhou, Yunxiao, Shen, Jie, Xia, Liqun, Wang, Yanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319226/
https://www.ncbi.nlm.nih.gov/pubmed/25663821
http://dx.doi.org/10.1186/s12935-014-0145-1