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Bioinformatic and mass spectrometry identification of Anaplasma phagocytophilum proteins translocated into host cell nuclei

Obligate intracellular bacteria have an arsenal of proteins that alter host cells to establish and maintain a hospitable environment for replication. Anaplasma phagocytophilum secrets Ankyrin A (AnkA), via a type IV secretion system, which translocates to the nucleus of its host cell, human neutroph...

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Detalles Bibliográficos
Autores principales: Sinclair, Sara H. G., Garcia-Garcia, Jose C., Dumler, J. Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319465/
https://www.ncbi.nlm.nih.gov/pubmed/25705208
http://dx.doi.org/10.3389/fmicb.2015.00055