Prolonged release melatonin for improving sleep in totally blind subjects: a pilot placebo-controlled multicenter trial

INTRODUCTION: Melatonin, secreted by the pineal gland during the night phase, is a regulator of the biological clock and sleep tendency. Totally blind subjects frequently report severe, periodic sleep problems, with 50%–75% of cases displaying non-24-hour sleep–wake disorder (N24HSWD) due to inabili...

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Detalles Bibliográficos
Autores principales: Roth, Thomas, Nir, Tali, Zisapel, Nava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319556/
https://www.ncbi.nlm.nih.gov/pubmed/25678831
http://dx.doi.org/10.2147/NSS.S71838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319556/
https://www.ncbi.nlm.nih.gov/pubmed/25678831
http://dx.doi.org/10.2147/NSS.S71838

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