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Prolonged release melatonin for improving sleep in totally blind subjects: a pilot placebo-controlled multicenter trial
INTRODUCTION: Melatonin, secreted by the pineal gland during the night phase, is a regulator of the biological clock and sleep tendency. Totally blind subjects frequently report severe, periodic sleep problems, with 50%–75% of cases displaying non-24-hour sleep–wake disorder (N24HSWD) due to inabili...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319556/ https://www.ncbi.nlm.nih.gov/pubmed/25678831 http://dx.doi.org/10.2147/NSS.S71838 |