Screening Nylon-3 Polymers, a New Class of Cationic Amphiphiles, for siRNA Delivery

[Image: see text] Amphiphilic nucleic acid carriers have attracted strong interest. Three groups of nylon-3 copolymers (poly-β-peptides) possessing different cationic/hydrophobic content were evaluated as siRNA delivery agents in this study. Their ability to condense siRNA was determined in SYBR Gol...

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Detalles Bibliográficos
Autores principales: Nadithe, Venkatareddy, Liu, Runhui, Killinger, Bryan A., Movassaghian, Sara, Kim, Na Hyung, Moszczynska, Anna B., Masters, Kristyn S., Gellman, Samuel H., Merkel, Olivia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319696/
https://www.ncbi.nlm.nih.gov/pubmed/25437915
http://dx.doi.org/10.1021/mp5004724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319696/
https://www.ncbi.nlm.nih.gov/pubmed/25437915
http://dx.doi.org/10.1021/mp5004724

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