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Screening Nylon-3 Polymers, a New Class of Cationic Amphiphiles, for siRNA Delivery
[Image: see text] Amphiphilic nucleic acid carriers have attracted strong interest. Three groups of nylon-3 copolymers (poly-β-peptides) possessing different cationic/hydrophobic content were evaluated as siRNA delivery agents in this study. Their ability to condense siRNA was determined in SYBR Gol...
Autores principales: | Nadithe, Venkatareddy, Liu, Runhui, Killinger, Bryan A., Movassaghian, Sara, Kim, Na Hyung, Moszczynska, Anna B., Masters, Kristyn S., Gellman, Samuel H., Merkel, Olivia M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319696/ https://www.ncbi.nlm.nih.gov/pubmed/25437915 http://dx.doi.org/10.1021/mp5004724 |
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