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The C-Type Lectin Receptor Mincle Binds to Streptococcus pneumoniae but Plays a Limited Role in the Anti-Pneumococcal Innate Immune Response

The innate immune system employs C-type lectin receptors (CLRs) to recognize carbohydrate structures on pathogens and self-antigens. The Macrophage-inducible C-type lectin (Mincle) is a FcRγ-coupled CLR that was shown to bind to mycobacterial cord factor as well as certain fungal species. However, s...

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Detalles Bibliográficos
Autores principales: Rabes, Anne, Zimmermann, Stephanie, Reppe, Katrin, Lang, Roland, Seeberger, Peter H., Suttorp, Norbert, Witzenrath, Martin, Lepenies, Bernd, Opitz, Bastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319728/
https://www.ncbi.nlm.nih.gov/pubmed/25658823
http://dx.doi.org/10.1371/journal.pone.0117022