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The C-Type Lectin Receptor Mincle Binds to Streptococcus pneumoniae but Plays a Limited Role in the Anti-Pneumococcal Innate Immune Response
The innate immune system employs C-type lectin receptors (CLRs) to recognize carbohydrate structures on pathogens and self-antigens. The Macrophage-inducible C-type lectin (Mincle) is a FcRγ-coupled CLR that was shown to bind to mycobacterial cord factor as well as certain fungal species. However, s...
Autores principales: | Rabes, Anne, Zimmermann, Stephanie, Reppe, Katrin, Lang, Roland, Seeberger, Peter H., Suttorp, Norbert, Witzenrath, Martin, Lepenies, Bernd, Opitz, Bastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319728/ https://www.ncbi.nlm.nih.gov/pubmed/25658823 http://dx.doi.org/10.1371/journal.pone.0117022 |
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