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Antrodin C Inhibits Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer Cells via Suppression of Smad2/3 and β-Catenin Signaling Pathways

Epithelial-to-mesenchymal transition (EMT) is a crucial event involved metastasis of certain tumors. Thus, identifying chemical agents that can block EMT is highly warranted for the development of anti-cancer chemoprevention/chemotherapies. In this study, we found that Antrodin C (ADC), a maleimide...

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Detalles Bibliográficos
Autores principales: Kumar, K. J. Senthil, Vani, M. Gokila, Chueh, Pin-Ju, Mau, Jeng-Leun, Wang, Sheng-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319743/
https://www.ncbi.nlm.nih.gov/pubmed/25658913
http://dx.doi.org/10.1371/journal.pone.0117111