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Proteasome 19S RP Binding to the Sec61 Channel Plays a Key Role in ERAD
Import of secretory proteins into the Endoplasmic Reticulum (ER) is an established function of the Sec61 channel. The contribution of the Sec61 channel to export of misfolded proteins from the ER for degradation by proteasomes is still controversial, but the proteasome 19S regulatory particle (RP) i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319758/ https://www.ncbi.nlm.nih.gov/pubmed/25658429 http://dx.doi.org/10.1371/journal.pone.0117260 |