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Transcription Driven Somatic DNA Methylation within the Imprinted Gnas Cluster

Differential marking of genes in female and male gametes by DNA methylation is essential to genomic imprinting. In female gametes transcription traversing differentially methylated regions (DMRs) is a common requirement for de novo methylation at DMRs. At the imprinted Gnas cluster oocyte specific t...

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Detalles Bibliográficos
Autores principales: Mehta, Stuti, Williamson, Christine M., Ball, Simon, Tibbit, Charlotte, Beechey, Colin, Fray, Martin, Peters, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319783/
https://www.ncbi.nlm.nih.gov/pubmed/25659103
http://dx.doi.org/10.1371/journal.pone.0117378