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CDK-1 and Two B-Type Cyclins Promote PAR-6 Stabilization during Polarization of the Early C. elegans Embryo

In the C. elegans embryo, formation of an antero-posterior axis of polarity relies on signaling by the conserved PAR proteins, which localize asymmetrically in two mutually exclusive groups at the embryonic cortex. Depletion of any PAR protein causes a loss of polarity and embryonic lethality. A gen...

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Detalles Bibliográficos
Autores principales: Rabilotta, Alexia, Desrosiers, Marianne, Labbé, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319824/
https://www.ncbi.nlm.nih.gov/pubmed/25658117
http://dx.doi.org/10.1371/journal.pone.0117656