Cancer-Associated Fibroblasts in a Human HEp-2 Established Laryngeal Xenografted Tumor Are Not Derived from Cancer Cells through Epithelial-Mesenchymal Transition, Phenotypically Activated but Karyotypically Normal

Cancer-associated fibroblasts (CAFs) play a crucial role in cancer progression and even initiation. However, the origins of CAFs in various cancer types remain controversial, and one of the important hypothesized origins is through epithelial-mesenchymal transition (EMT) from cancer cells. In this s...

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Detalles Bibliográficos
Autores principales: Wang, Mei, Wu, Chun-Ping, Pan, Jun-Yan, Zheng, Wen-Wei, Cao, Xiao-Juan, Fan, Guo-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319834/
https://www.ncbi.nlm.nih.gov/pubmed/25658113
http://dx.doi.org/10.1371/journal.pone.0117405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319834/
https://www.ncbi.nlm.nih.gov/pubmed/25658113
http://dx.doi.org/10.1371/journal.pone.0117405

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