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Identification of Synaptosomal Proteins Binding to Monomeric and Oligomeric α-Synuclein

Monomeric α-synuclein (αSN) species are abundant in nerve terminals where they are hypothesized to play a physiological role related to synaptic vesicle turn-over. In Parkinson’s disease (PD) and dementia with Lewy body (DLB), αSN accumulates as aggregated soluble oligomers in terminals, axons and t...

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Detalles Bibliográficos
Autores principales: Betzer, Cristine, Movius, A. James, Shi, Min, Gai, Wei-Ping, Zhang, Jing, Jensen, Poul Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319895/
https://www.ncbi.nlm.nih.gov/pubmed/25659148
http://dx.doi.org/10.1371/journal.pone.0116473