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Serpin Treatment Suppresses Inflammatory Vascular Lesions in Temporal Artery Implants (TAI) from Patients with Giant Cell Arteritis

Giant cell arteritis (GCA) and Takayasu’s disease are inflammatory vasculitic syndromes (IVS) causing sudden blindness and widespread arterial obstruction and aneurysm formation. Glucocorticoids and aspirin are mainstays of treatment, predominantly targeting T cells. Serp-1, a Myxomavirus-derived se...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Zheng, Donghang, Ambadapadi, Sriram, Davids, Jennifer, Ryden, Sally, Samy, Hazem, Bartee, Mee, Sobel, Eric, Dai, Erbin, Liu, Liying, Macaulay, Colin, Yachnis, Anthony, Weyand, Cornelia, Thoburn, Robert, Lucas, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319900/
https://www.ncbi.nlm.nih.gov/pubmed/25658487
http://dx.doi.org/10.1371/journal.pone.0115482