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Serpin Treatment Suppresses Inflammatory Vascular Lesions in Temporal Artery Implants (TAI) from Patients with Giant Cell Arteritis
Giant cell arteritis (GCA) and Takayasu’s disease are inflammatory vasculitic syndromes (IVS) causing sudden blindness and widespread arterial obstruction and aneurysm formation. Glucocorticoids and aspirin are mainstays of treatment, predominantly targeting T cells. Serp-1, a Myxomavirus-derived se...
Autores principales: | Chen, Hao, Zheng, Donghang, Ambadapadi, Sriram, Davids, Jennifer, Ryden, Sally, Samy, Hazem, Bartee, Mee, Sobel, Eric, Dai, Erbin, Liu, Liying, Macaulay, Colin, Yachnis, Anthony, Weyand, Cornelia, Thoburn, Robert, Lucas, Alexandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319900/ https://www.ncbi.nlm.nih.gov/pubmed/25658487 http://dx.doi.org/10.1371/journal.pone.0115482 |
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