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Alpha 1-Antitrypsin Does Not Inhibit Human Monocyte Caspase-1
BACKGROUND: Alpha 1-antitrypsin (A1AT) is a 52 kDa serine protease inhibitor produced largely by hepatocytes but also by mononuclear phagocytes. A1AT chiefly inhibits neutrophil elastase and proteinase-3 but has also been reported to have immune modulatory functions including the ability to inhibit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319913/ https://www.ncbi.nlm.nih.gov/pubmed/25658455 http://dx.doi.org/10.1371/journal.pone.0117330 |