WIP1 Phosphatase as a Potential Therapeutic Target in Neuroblastoma

The wild-type p53-induced phosphatase 1 (WIP1) is a serine/threonine phosphatase that negatively regulates multiple proteins involved in DNA damage response including p53, CHK2, Histone H2AX, and ATM, and it has been shown to be overexpressed or amplified in human cancers including breast and ovaria...

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Detalles Bibliográficos
Autores principales: Richter, Mark, Dayaram, Tajhal, Gilmartin, Aidan G., Ganji, Gopinath, Pemmasani, Sandhya Kiran, Van Der Key, Harjeet, Shohet, Jason M., Donehower, Lawrence A., Kumar, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319922/
https://www.ncbi.nlm.nih.gov/pubmed/25658463
http://dx.doi.org/10.1371/journal.pone.0115635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319922/
https://www.ncbi.nlm.nih.gov/pubmed/25658463
http://dx.doi.org/10.1371/journal.pone.0115635

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