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Autoregulation and Heterogeneity in Expression of Human Cripto-1

Cripto-1 (CR-1) is involved in various processes in embryonic development and cancer. Multiple pathways regulate CR-1 expression. Our present work demonstrates a possible positive feedback circuit where CR-1 induces its own expression. Using U-87 MG cells treated with exogenous CR-1, we show that su...

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Detalles Bibliográficos
Autores principales: Loying, Pojul, Manhas, Janvie, Sen, Sudip, Bose, Biplab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319928/
https://www.ncbi.nlm.nih.gov/pubmed/25658584
http://dx.doi.org/10.1371/journal.pone.0116748