SMAD-Independent Down-Regulation of Caveolin-1 by TGF-β: Effects on Proliferation and Survival of Myofibroblasts

Transforming growth factor-β (TGF-β) mediates growth-inhibitory effects on most target cells via activation of the canonical SMAD signaling pathway. This growth-inhibitory activity may be coupled with cellular differentiation. Our studies demonstrate that TGF-β1 inhibits proliferation of primary, no...

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Detalles Bibliográficos
Autores principales: Sanders, Yan Y., Cui, Zongbin, Le Saux, Claude Jourdan, Horowitz, Jeffrey C., Rangarajan, Sunad, Kurundkar, Ashish, Antony, Veena B., Thannickal, Victor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319960/
https://www.ncbi.nlm.nih.gov/pubmed/25658089
http://dx.doi.org/10.1371/journal.pone.0116995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319960/
https://www.ncbi.nlm.nih.gov/pubmed/25658089
http://dx.doi.org/10.1371/journal.pone.0116995

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