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SMAD-Independent Down-Regulation of Caveolin-1 by TGF-β: Effects on Proliferation and Survival of Myofibroblasts
Transforming growth factor-β (TGF-β) mediates growth-inhibitory effects on most target cells via activation of the canonical SMAD signaling pathway. This growth-inhibitory activity may be coupled with cellular differentiation. Our studies demonstrate that TGF-β1 inhibits proliferation of primary, no...
Autores principales: | Sanders, Yan Y., Cui, Zongbin, Le Saux, Claude Jourdan, Horowitz, Jeffrey C., Rangarajan, Sunad, Kurundkar, Ashish, Antony, Veena B., Thannickal, Victor J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319960/ https://www.ncbi.nlm.nih.gov/pubmed/25658089 http://dx.doi.org/10.1371/journal.pone.0116995 |
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