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SRSF1 Facilitates Cytosolic DNA-Induced Production of Type I Interferons Recognized by RIG-I

BACKGROUND: Evidence has shown that psoriasis is closely associated with infection; however, the mechanism of this association remains unclear. In mammalian cells, viral or bacterial infection is accompanied by the release of cytosolic DNA, which in turn triggers the production of type-I interferons...

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Detalles Bibliográficos
Autores principales: Xue, Feng, Li, Xia, Zhao, Xiaoqing, Wang, Lanqi, Liu, Min, Shi, Ruofei, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319963/
https://www.ncbi.nlm.nih.gov/pubmed/25658361
http://dx.doi.org/10.1371/journal.pone.0115354