Calpain-3 Impairs Cell Proliferation and Stimulates Oxidative Stress-Mediated Cell Death in Melanoma Cells

Calpain-3 is an intracellular cysteine protease, belonging to Calpain superfamily and predominantly expressed in skeletal muscle. In human melanoma cell lines and biopsies, we previously identified two novel splicing variants (hMp78 and hMp84) of Calpain-3 gene (CAPN3), which have a significant lowe...

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Detalles Bibliográficos
Autores principales: Moretti, Daniele, Del Bello, Barbara, Allavena, Giulia, Corti, Alessandro, Signorini, Cinzia, Maellaro, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319969/
https://www.ncbi.nlm.nih.gov/pubmed/25658320
http://dx.doi.org/10.1371/journal.pone.0117258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319969/
https://www.ncbi.nlm.nih.gov/pubmed/25658320
http://dx.doi.org/10.1371/journal.pone.0117258

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