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Calpain-3 Impairs Cell Proliferation and Stimulates Oxidative Stress-Mediated Cell Death in Melanoma Cells
Calpain-3 is an intracellular cysteine protease, belonging to Calpain superfamily and predominantly expressed in skeletal muscle. In human melanoma cell lines and biopsies, we previously identified two novel splicing variants (hMp78 and hMp84) of Calpain-3 gene (CAPN3), which have a significant lowe...
Autores principales: | Moretti, Daniele, Del Bello, Barbara, Allavena, Giulia, Corti, Alessandro, Signorini, Cinzia, Maellaro, Emilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319969/ https://www.ncbi.nlm.nih.gov/pubmed/25658320 http://dx.doi.org/10.1371/journal.pone.0117258 |
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