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Structure-Inherent Targeting of NIR Fluorophores for Parathyroid and Thyroid Gland Imaging

The typical method for creating targeted contrast agents requires covalent conjugation of separate targeting and fluorophore domains. In this study, we demonstrate that it is possible create tissue-specific near-infrared fluorophores using the inherent chemical structure. Thus, a single compact mole...

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Detalles Bibliográficos
Autores principales: Hyun, Hoon, Park, Min Ho, Owens, Eric A., Wada, Hideyuki, Henary, Maged, Handgraaf, Hein J.M., Vahrmeijer, Alexander L., Frangioni, John V., Choi, Hak Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319985/
https://www.ncbi.nlm.nih.gov/pubmed/25559343
http://dx.doi.org/10.1038/nm.3728