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Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase
Biotin-dependent carboxylases are widely distributed in nature and have important functions in the metabolism of fatty acids, amino acids, carbohydrates, cholesterol and other compounds (1–6). Defective mutations in several of these enzymes have been linked to serious metabolic diseases in humans, a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319993/ https://www.ncbi.nlm.nih.gov/pubmed/25383525 http://dx.doi.org/10.1038/nature13912 |