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Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase

Biotin-dependent carboxylases are widely distributed in nature and have important functions in the metabolism of fatty acids, amino acids, carbohydrates, cholesterol and other compounds (1–6). Defective mutations in several of these enzymes have been linked to serious metabolic diseases in humans, a...

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Detalles Bibliográficos
Autores principales: Tran, Timothy H., Hsiao, Yu-Shan, Jo, Jeanyoung, Chou, Chi-Yuan, Dietrich, Lars E.P., Walz, Thomas, Tong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319993/
https://www.ncbi.nlm.nih.gov/pubmed/25383525
http://dx.doi.org/10.1038/nature13912